Actively Recruiting
Risk Factors for Hepatic Inflammation, Fibrosis and Prognosis in Patients With CHB and NAFLD
Led by The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Updated on 2023-03-13
1000
Participants Needed
1
Research Sites
256 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Chronic hepatitis B (CHB) affects an estimated 292 million people, and causes approximately 800,000 people deaths per year from liver-related complications including cirrhosis and hepatocellular carcinoma, remaining a major global public health issue.Meanwhile, with the improvement of living standards and changes in lifestyle and dietary habits, non-alcoholic fatty liver disease (NAFLD) has become another important cause of liver cirrhosis and HCC.HBV combined with NAFLD inevitably develops into continuous or intermittent liver inflammation and fibrosis, which greatly increases the risk of cirrhosis, liver cancer and even end-stage liver disease. We aimed to investigate the risk factors and establish diagnostic models for hepatic inflammation, fibrosis in patients with CHB associated NAFLD. In addition, to find risk factors for liver cirrhosis, liver cancer or liver failure in patients with CHB-related NAFLD.
CONDITIONS
Official Title
Risk Factors for Hepatic Inflammation, Fibrosis and Prognosis in Patients With CHB and NAFLD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years or older
- Positive hepatitis B surface antigen (HBsAg) for at least 6 months without other viral co-infection at baseline
- Non-alcoholic fatty liver disease (NAFLD) diagnosed by imaging, liver biopsy, and/or blood testing or predictive indices
You will not qualify if you...
- Presence of other chronic liver diseases such as alcoholic liver disease, other viral hepatitis, or drug-induced liver injury
- Diagnosis of hepatocellular carcinoma (HCC) or other malignancies before liver biopsy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Nanjing Drum Tower Hospital
Nanjing, China
Actively Recruiting
Research Team
J
Jie Li, M.D., Ph.D
CONTACT
F
Fajuan Rui
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here