Actively Recruiting
Risk Factors for Microvascular Obstruction Post-Emergency PCI in AMI Patients
Led by The Third Xiangya Hospital of Central South University · Updated on 2025-07-02
300
Participants Needed
1
Research Sites
65 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this prospective cohort study is to investigate the relationship between the TyG index and early identification of MVO in AMI patients undergoing emergency PCI and CMR imaging. The study will enroll approximately 300 AMI patients treated at Xiangya Third Hospital of Central South University from June 2024 to August 2025. The main questions it aims to answer are: * How does the TyG index correlate with the early detection of MVO? * What differences in cardiovascular adverse events during hospitalization exist between groups with varying TyG index levels? Participants will undergo emergency PCI and CMR imaging within 3-7 days post-procedure. Data collected will include demographic characteristics, clinical history, coronary angiography data, laboratory test indicators (especially metabolic markers such as blood glucose and lipids), IVUS-related plaque information, and CMR results.
CONDITIONS
Official Title
Risk Factors for Microvascular Obstruction Post-Emergency PCI in AMI Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- STEMI symptom onset less than 12 hours ago
- STEMI symptom onset 12 to 48 hours ago with ongoing ischemic symptoms, hemodynamic instability, or life-threatening ventricular arrhythmias
- Very high-risk NSTEMI patients undergoing emergency PCI treatment
- Voluntary signed informed consent form
You will not qualify if you...
- Non-obstructive acute myocardial infarction
- Severe chronic kidney disease with estimated glomerular filtration rate less than 20 mL/min per 1.73 m²
- Pregnant women or those planning to become pregnant
- Failure of emergency PCI
- Unclear cardiac magnetic resonance (CMR) images
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Xiangya Third Hospital of Central South University
Changsha, Hunan Province,China, China, 410013
Actively Recruiting
Research Team
C
can Zhu Can
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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