Actively Recruiting
The Risk Factors Related to Rupture Flow-related Aneurysms in Posterior AVM
Led by The First Affiliated Hospital with Nanjing Medical University · Updated on 2025-07-03
200
Participants Needed
2
Research Sites
80 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
AVMs have been reported to rupture at a formidable annual rate of 2% to 3% at natural progression, often resulting in longterm neurological deficits and poor functional outcomes.The reported risk of hemorrhagic presentation in patients with AVMs is 41% to 65%. While many studies suggest a correlation between higher hemorrhage risk and the concurrent presence of AVM and aneurysms, few authors have focused specifically on flow-related aneurysms alone. In many instances, the source of rupture is also unclear. Meta-analysis from 2016 suggested that 49.2% of hemorrhages were secondary to aneurysm rupture, 45% from AVM rupture, and 5.7% were undetermined.In a study of 302 patients, of which 52.6% had a hemorrhagic presentation, demonstrated a significant increase in rate of hemorrhage in those with flow-related aneurysms. Thus, it is necessary to figure out risk factors related to ruptured flow-related aneurysms in pAVM.
CONDITIONS
Official Title
The Risk Factors Related to Rupture Flow-related Aneurysms in Posterior AVM
Who Can Participate
Eligibility Criteria
You may qualify if you...
- pAVM with flow-related aneurysms identified by DSA
- Subarachnoid hemorrhage confirmed by CT
- No history of stroke
- No Marfan syndrome
- No polycystic kidney disease
You will not qualify if you...
- pAVM without flow-related aneurysms
- Absence of clinical data
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Jiangsu Province Hospital
Nanjing, Jiangsu, China, 225500
Active, Not Recruiting
2
the First Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China
Actively Recruiting
Research Team
Y
Yifei Wang
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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