Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06949579

Risk of Posterior Staphyloma in Highly Myopic Europeans : From Epidemiology to Anatomy.

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-03-31

200

Participants Needed

1

Research Sites

95 weeks

Total Duration

On this page

Sponsors

A

Assistance Publique - Hôpitaux de Paris

Lead Sponsor

U

URC-CIC Paris Descartes Necker Cochin

Collaborating Sponsor

AI-Summary

What this Trial Is About

In this cross-sectionnal study the aim is to increase the understanding of posterior staphyloma through a unique European consortium. Therefore, all eligible patients that either visit the outpatient clinic at Radboud in Nimegen, the Netherlands, or visit University Hopital Puerta de HierroMajadahonda in Madrid, Spain, or visit University Hospital Cochin in Paris, France, and after consenting, will be included. 600 high myopic European cases are expecting. A standardized protocol in all centers in order to create a uniform dataset. Besides the standard of care, blood samples will be collected. All data collected will be stored in an onlie Castor database

CONDITIONS

Official Title

Risk of Posterior Staphyloma in Highly Myopic Europeans : From Epidemiology to Anatomy.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older
  • High myopia with axial length 26 26.00 mm or degree of myopia of at least -6 diopters
  • Good quality retinal imaging available
  • Signed consent form to participate in the study
  • Beneficiary of or entitled to a social security scheme
Not Eligible

You will not qualify if you...

  • Any systemic disease likely to affect the posterior segment of the eye
  • Diabetes
  • Systemic inflammatory diseases such as sarcoidosis, rheumatoid arthritis, systemic lupus erythematosus, or Horton's disease
  • Retinitis pigmentosa
  • Syndromic myopia
  • Myopia associated with genetic diseases like hereditary vitreoretinopathy
  • Under guardianship, curatorship, or legal protection
  • Pregnant or breastfeeding women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cochin Hospital

Paris, France, 75014

Actively Recruiting

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Research Team

F

Francine Behar-Cohen, MD, PhD

CONTACT

V

Valérie PLENCE, Msc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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