Actively Recruiting
Risk Stratification of MACE Based on GDF-15 in Heart Failure Patients Who Undergoing Coronary Artery Bypass Grafting: an Observational Multicenter Prospective Study
Led by Tomsk National Research Medical Center of the Russian Academy of Sciences · Updated on 2026-03-18
160
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
PROFILE-HF is a multicenter, observational, prospective study of the clinical course and outcomes of chronic heart failure (HF) and coronary artery disease (CAD) in patients undergoing coronary artery bypass grafting (CABG). The objective of the study is to develop a method for assessing the risk of adverse cardiovascular events in patients with CAD and HF who have undergone CABG, based on preoperative GDF-15 concentrations. The study will have a 12-month follow-up period; one in-person visit is planned at the end of the follow-up period. If it is not possible to visit a doctor in person, information will be collected through telephone contact with the patient or his relative or person caring for the patient.
CONDITIONS
Brief Title
Risk Stratification of MACE in Heart Failure Patients Who Undergoing CABG
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Heart Failure
- Planned coronary artery bypass grafting
You will not qualify if you...
- Myocardial infarction
- Stroke
- Presence of implanted devices;
- Need for additional cardiac surgery other than coronary artery bypass grafting (valve repair, aneurysm);
- Severe renal dysfunction (GFR <30 ml/min/1.73 m2);
- Severe comorbidities: active cancer; infiltrative cardiac diseases (sarcoidosis, amyloidosis, storage diseases); autoimmune diseases; acute infectious diseases and exacerbations of chronic somatic diseases.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Cardiology Research Institute, Tomsk National Research Medical Center Russian Academy of Sciences
Tomsk, Tomsk Oblast, Russia, 634050
Actively Recruiting
Research Team
A
Alla A. Garganeeva, MD, PhD
E
Elena A. Kuzheleva, MD, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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