Actively Recruiting
Ritual Synbiotic+, a Dietary Supplement Designed to Impact Gastrointestinal Health, Mood, and Behavior in Women
Led by Colorado State University · Updated on 2025-11-14
60
Participants Needed
1
Research Sites
34 weeks
Total Duration
On this page
Sponsors
C
Colorado State University
Lead Sponsor
R
Ritual
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of this study is to determine how regular consumption of Synbiotic+, a dietary supplement that contains prebiotics, probiotics, and postbiotics, impacts functional gastrointestinal health, markers of intestinal inflammation and immune health, and influences mood and behavior. The primary outcome will be to assess gastrointestinal health using bowel movement tracking, self-report and objective assessments of gastrointestinal symptom severity, stool levels of short chain fatty acids, changes in the gut microbiota, including recovery of LGG and BB-12, and functional measures of the microbiome. Secondary outcomes will include stool and blood markers of gut barrier function and intestinal inflammation, immune health, and self-assessments of stress, anxiety, sleep, and quality of life.
CONDITIONS
Official Title
Ritual Synbiotic+, a Dietary Supplement Designed to Impact Gastrointestinal Health, Mood, and Behavior in Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy adult women aged 25 to 65 years
- BMI less than 30
- Moderate gastrointestinal symptoms
- Willingness to follow the study protocol and attend clinic visits
You will not qualify if you...
- Age younger than 25 years or older than 65 years
- BMI greater than 30
- Antibiotic use within two months or probiotic use within 14 days before treatment
- Use of medications or supplements that may affect study results, including statins, metformin, NSAIDs, MAO inhibitors, and hormone therapies
- Current diagnosis of cancer, liver or kidney disease, gastrointestinal diseases, or cardiometabolic disorders
- Pregnant or breastfeeding
- Excessive alcohol use based on self-report
- Inability to adhere to study requirements including capsule intake, sample collection, symptom tracking, and clinic visits
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Colorado State University Food and Nutrition Clinical Research Laboratory
Fort Collins, Colorado, United States, 80523
Actively Recruiting
Research Team
D
Dr. Tiffany Weir, PhD
CONTACT
J
Jenny Whittington, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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