Actively Recruiting
The ROAR Study: Reactive Oxygen Species and Reproduction
Led by University of California, San Francisco · Updated on 2026-02-17
1100
Participants Needed
1
Research Sites
86 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a prospective cohort study characterizing follicular fluid and serum levels of oxidative stress in women with various infertility diagnoses undergoing in vitro fertilization, and assessing the relationship of oxidative stress to oocyte competence as determined by embryo development outcomes. Furthermore, we will measure oxidative stress in sperm and correlate the overall oxidative stress within the couple with IVF and pregnancy outcomes of the resultant embryos.
CONDITIONS
Official Title
The ROAR Study: Reactive Oxygen Species and Reproduction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female age 18-43 years
- Subjects planning blastocyst culture for preimplantation genetic screening (PGS) for aneuploidy
- Male partners 18 years of age or older
- Must be a registered patient at UCSF Center for Reproductive Health
- Patient and partner must both be physically present on the day of retrieval
You will not qualify if you...
- Female partner age 44 or older
- Planning fresh transfer (hybrid PGS cycle)
- Cleavage stage biopsy
- Planning to use frozen sperm
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California, San Francisco
San Francisco, California, United States, 94158
Actively Recruiting
Research Team
E
Elena Hoskin, BS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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