Actively Recruiting
Robot-assisted Function-sparing Cystectomy Followed by Modified Orthotopic Ileal Neobladder
Led by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Updated on 2024-05-13
20
Participants Needed
1
Research Sites
82 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
With the same tumor control rate as classic radical cystectomy, radical cystectomy with partial preservation of the prostate and seminal vesicle can effectively preserve penile erection and fertility, improve urinary control rate and shorten hospitalization time. In this project, transurethral resection of the prostate was used to remove part of the prostate, which further reduced the trauma of radical cystectomy and better preserved the nerves and urethral sphincter. Rapid intraoperative examination of resected tissue can provide a basis for the selection of surgical options. Robot-assisted radical cystectomy can perform pelvic lymph node dissection more accurately, preserve neurovascular complex more effectively, and improve the control effect of tumor and the protective effect of sexual function and reproductive function. In view of the shortcomings of the internationally accepted orthotopic ileal neobladder, this study improved the operation according to the physiological and anatomical characteristics, restored the orthophoria of the new bladder, maintained the consistency of physiological anatomy, and minimized the bladder pressure.
CONDITIONS
Official Title
Robot-assisted Function-sparing Cystectomy Followed by Modified Orthotopic Ileal Neobladder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Muscle invasive or recurrent multiple non-muscle invasive bladder cancer patients
- Invasive bladder cancer patients without invasion of the triangle and posterior urethra
- Male patients younger than 70 years with good urethral sphincter function
- Serum prostate specific antigen less than 4 µg/L
You will not qualify if you...
- Possible urethral recurrence after cystectomy
- Bladder adenocarcinoma or squamous cell carcinoma patients ineligible for orthotopic neobladder
- Patients with renal insufficiency
- Patients with severe liver dysfunction
- Patients with severe intestinal diseases such as Crohn's disease or short bowel syndrome
- Preoperative tumor invasion beyond the bladder into surrounding tissue
- Urethral stricture preventing passage of the resectoscope
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Union hospital,Tongji medical college, Huazhong university of science and techonology
Wuhan, Hubei, China, 430022
Actively Recruiting
Research Team
X
Xiaoping Zhang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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