Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06273475

Robot-Assisted Training Versus Standard Training in Ischemic Stroke

Led by Odense University Hospital · Updated on 2025-11-20

40

Participants Needed

2

Research Sites

143 weeks

Total Duration

On this page

Sponsors

O

Odense University Hospital

Lead Sponsor

U

University of Southern Denmark

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of this randomised controlled trial (RCT) nested in a prospective cohort, is to investigate the superior effect of late-phase robot-assisted versus standard training on motor function, physical function, fatigue, and quality of life in a moderately-to-severely impaired chronic stroke population following subacute rehabilitation. The main hypothesis of the study is: Robot-assisted training has a superior effect on motor function (Fugl-Meyer Lower Extremity Assessment; primary outcome), physical function, fatigue, and quality of life in moderately-to-severely impaired chronic stroke-affected individuals in comparison to standard training.

CONDITIONS

Official Title

Robot-Assisted Training Versus Standard Training in Ischemic Stroke

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with ischemic or hemorrhagic stroke
  • Between 6 and 24 months post-stroke (chronic phase)
  • Completed subacute rehabilitation phase (up to 6 months post-stroke)
  • Moderate to severe impairment with Modified Rankin Scale score 3-5
  • Scandinavian Stroke Scale leg motor function score 0-4 and/or gait function score 0-9
  • Approved by referring doctor
Not Eligible

You will not qualify if you...

  • Prior subarachnoid hemorrhage (SAH)
  • Stroke infarct located in the cerebellum or brain stem
  • Severe fatigue making study completion unlikely
  • Cognitive deficits that prevent participation
  • Inability to walk independently before stroke
  • Recurrence of cardiovascular or cerebrovascular events
  • Pre-existing neurological diseases or ongoing cancer treatment
  • Refusal of group allocation
  • Participation in another clinical trial that could interfere with this study

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Rigshospitalet and Herlev Gentofte Hospital

Copenhagen, Denmark

Not Yet Recruiting

2

Odense University Hospital

Odense, Denmark

Actively Recruiting

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Research Team

J

Jon Skovgaard Jensen, Ph.d.-student

CONTACT

A

Anders Holsgaard-Larsen, Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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