Actively Recruiting
Robot-assisted Walking Treatment in Hereditary Spastic Paraplegia (HSP)
Led by IRCCS Eugenio Medea · Updated on 2025-05-04
50
Participants Needed
1
Research Sites
782 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients will undergo a combined rehabilitation treatment consisting of 15 sessions on Lokomat and 15 sessions of physical therapy over three weeks for a total of 30 sessions. Two sessions/day for 5 days a week. The same subjects will conduct clinical-functional assessments before, at the end of treatment, and after a 3-month follow-up: 3D Gait Analysis with defined protocol (BTSBioenginner); Spastic Paraplegia Rating Scale (SPRS); Six-Minute Walk Test (6MWT), Ten Meters Walk Test (10MWT), Gross Motor Function Measure-88 (GMFM-88) and Berg Balance Scale (BBS); Quality of life questionnaires: Medical Outcome Survey Short Form (SF-36) and ad hoc questionnaire for subjective assessment of symptoms during walking (HSP-SNAP). This study is part of normal clinical practice and does not involve any changes to the current rehabilitation course for patients.
CONDITIONS
Official Title
Robot-assisted Walking Treatment in Hereditary Spastic Paraplegia (HSP)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Genetic or clinical diagnosis of Hereditary Spastic Paraplegia (HSP)
- Age greater than 4 years and less than 70 years
- Femur length greater than 23 cm
- Ability to walk independently indoors, with or without walking aids
You will not qualify if you...
- Botulinum toxin injection or lower limb surgery within the previous 6 months
- Severe lower limb muscle contractures
- Severe osteoporosis
- Unhealed skin lesions on lower limbs
- Cardiovascular instability
- Acute or progressive neurological disorders
- Behavioral problems
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Irccs Eugenio Medea
Bosisio Parini, Italy/lecco, Italy
Actively Recruiting
Research Team
E
ELEONORA DIELLA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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