Actively Recruiting
Robotic-assisted Bronchoscopy Under Moderate Sedation With Propofol: A Single-center Pilot Study
Led by University of Zurich · Updated on 2025-09-22
30
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating whether robotic-assisted bronchoscopy can be safely and effectively performed under moderate sedation with propofol, instead of the general anesthesia currently required. This pilot study aims to gather initial information on this approach before considering a larger trial. The focus is on patients scheduled for bronchoscopy to obtain lung tissue samples, particularly those with lung lesions. Participants will undergo a robotic-assisted bronchoscopy performed under moderate sedation using propofol. This approach is common for manual bronchoscopies but has not been tested extensively with robotic assistance. The study will assess the feasibility of combining the robotic technique with propofol sedation and will be conducted at a single center. During the procedure, researchers will confirm the placement of tools within the lung lesion and collect at least one tissue sample for histological analysis. They will monitor procedure duration, diagnostic accuracy for malignancy, and safety outcomes up to three months after treatment. Participants will have periinterventional laboratory exams and be followed closely for any adverse events, with the total observation period extending to eight days for most outcomes and three months for malignancy diagnosis.
CONDITIONS
Brief Title
Robotic-assisted Bronchoscopy Under Moderate Sedation With Propofol
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent by the participant
- At least 18 years old
- Scheduled for bronchoscopy with moderate sedation and tracheal intubation to obtain at least one lung tissue specimen via transbronchial biopsy
- Undergo necessary periinterventional laboratory exams for bronchoscopy
- Judged suitable by the investigator
You will not qualify if you...
- Presence of an endobronchial lesion causing lobar atelectasis
- Inability or contraindications to undergo bronchoscopy (e.g., severe heart or lung diseases, blood clotting disorders, intolerance to anesthesia or endoscopic procedures, psychiatric disorders or severe neurosis)
- Pregnant or breastfeeding women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of the procedure
Participants undergo robotic-assisted bronchoscopy under moderate sedation with propofol to obtain lung tissue samples for diagnosis.
1 visit (in-person)
Duration - Up to 3 months
Participants are monitored for diagnostic accuracy and safety outcomes after the bronchoscopy procedure.
Follow-up visits as scheduled up to 3 months
Trial Site Locations
Total: 1 location
1
University Hospital Zurich
Zurich, Canton of Zurich, Switzerland, 8091
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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