Actively Recruiting
Robotic Hemi-Prostatectomy With Urethral Preservation in Low and Intermediate Risk Monolateral Prostate Cancer
Led by Fondazione del Piemonte per l'Oncologia · Updated on 2023-09-26
36
Participants Needed
1
Research Sites
285 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
On the basis of the now consolidated literature and clinical experience of focal therapies, the execution of partial prostatectomy/hemiprostatectomy with robot-assisted laparoscopic technique can be proposed in a well-selected cohort of patients. The hypothesis is that with this technique it is possible to achieve excellent levels of disease control, in terms of positive surgical margins (PSM) and biochemical recurrence of the disease (BCR), against a minimal impact as regards postoperative functional outcomes (continence and sexual power).
CONDITIONS
Official Title
Robotic Hemi-Prostatectomy With Urethral Preservation in Low and Intermediate Risk Monolateral Prostate Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent and consent for use of personal data
- Prostate Specific Antigen (PSA) less than 20 ng/mL
- Unilateral organ-confined prostate cancer on MRI or PET-PSMA imaging
- Histological diagnosis of unilateral acinar-type prostate cancer with ISUP grade less than 3 on biopsy
- Eastern Cooperative Oncology Group (ECOG) performance status 0-1
- Life expectancy of at least 5 years
- Availability of pre-operative clinical data
- Willingness to attend follow-up visits as defined by the protocol
- No retroperitoneal, lymph node, bone, or visceral metastases
- Eligibility for robot-assisted radical prostatectomy
You will not qualify if you...
- Special histological types of prostate cancer
- PSA greater than 20 ng/mL at diagnosis
- Inability to undergo MRI or PET-PSMA (e.g., due to pacemaker or claustrophobia)
- Previous prostate surgery such as TURP or adenomectomy
- Current treatment with other anti-cancer drugs including investigational endocrine therapies
- Serious underlying disease or uncontrolled medical conditions including active infections
- Dementia or psychiatric illness limiting compliance or ability to consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fondazione del Piemonte per l'Oncologia
Candiolo, TO, Italy, 10060
Actively Recruiting
Research Team
F
Francesco Porpiglia
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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