Actively Recruiting
Robustness Evaluation of Deep Inspiration Breath-Hold (DIBH) Plans in Internal Mammary Irradiation
Led by Ruijin Hospital · Updated on 2026-03-27
25
Participants Needed
1
Research Sites
86 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is an investigator-initiated, single-arm, single-center, prospective, observational study. The hypothesis is that during the implementation of deep inspiration breath-hold (DIBH) radiotherapy plans in postoperative breast cancer patients receiving internal mammary irradiation, the actual target dose coverage and organ-at-risk (OARs) dose parameters remain within clinically acceptable ranges.
CONDITIONS
Official Title
Robustness Evaluation of Deep Inspiration Breath-Hold (DIBH) Plans in Internal Mammary Irradiation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed and dated informed consent form before any trial-specific procedures
- Female patients aged 18 years or older
- Histologically confirmed invasive breast cancer
- Breast-conserving surgery or mastectomy with axillary staging including sentinel lymph node biopsy and/or axillary lymph node dissection
- Able to hold breath for more than 30 seconds after deep inspiration
- Planned postoperative radiotherapy targeting regional lymph nodes including internal mammary nodes under DIBH
- Planned moderate hypofractionated radiotherapy
- Karnofsky Performance Status score of 80 or higher
- Estimated life expectancy greater than 5 years
- Sufficient wound healing from surgery with no active infection at radiation site
You will not qualify if you...
- Pregnant or breastfeeding women
- Severe, uncontrolled medical conditions that make participation unsuitable or affect protocol compliance
- Unable to understand or comply with breath-hold training instructions
- Right-sided breast cancer
AI-Screening
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Trial Site Locations
Total: 1 location
1
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Shanghai, Shanghai Municipality, China, 200025
Actively Recruiting
Research Team
L
Lu Cao, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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