Study on Antibiotic Use to Reduce Wound Infections After Open Repair of Primary Elective Groin Hernias in High-Risk Adults

What this Trial Is About

Researchers are evaluating the impact of antibiotic prophylaxis on reducing wound infection rates after open repair surgery for primary elective groin hernias in high-risk patients. This randomized controlled trial focuses on patients considered high risk due to factors like age, diabetes, obesity, immune system status, or other health issues. The study aims to determine if giving antibiotics before surgery lowers the chance of wound infections and related complications. Participants will be randomly assigned to one of two groups one group will receive a single preoperative dose of the antibiotic Cefazolin 1 gram, while the other group will not receive any antibiotic prophylaxis. The study compares these groups to assess the effectiveness of antibiotic use in preventing postoperative wound infections following the hernia repair surgery. During the study, participants will be monitored for up to 30 days after surgery for any wound or surgical site infections and overall complications. Researchers will also track secondary outcomes such as mortality rates and length of hospital stay. The study involves regular follow-up visits to assess recovery and any adverse events, ensuring safety and accurate data collection throughout the 30-day postoperative period.

The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients