Actively Recruiting
The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Observational)
Led by Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health · Updated on 2025-08-08
250
Participants Needed
1
Research Sites
452 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study is aimed at the investigation of the association of biomarkers of circadian rhythms with sleep characteristics and stroke outcome in acute stroke patients. It is designed as an observational cohort study with the retrospective and prospective longitudinal arms.
CONDITIONS
Official Title
The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Observational)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Acute ischemic stroke with symptom onset to admission less than 1 day
- Ischemic stroke affecting branches of the anterior, middle, or posterior cerebral artery
- Age between 18 and 80 years
- Moderate or severe stroke with NIH Stroke Scale score of 5 or higher
- Received intravascular stroke treatment with thrombolysis or thrombectomy leading to satisfactory reperfusion if applicable
- Provided informed consent
You will not qualify if you...
- Secondary parenchymal hemorrhage with hemorrhage index greater than 2
- Clinically unstable or life-threatening conditions
- Known progressive neurological diseases
- Known psychiatric diseases
- Current use of benzodiazepine medication
- Drug or alcohol abuse
- Pregnancy
- Disability preventing participation in the study
- Congestive heart failure with reduced ejection fraction (45% or less) or NYHA class III-IV
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Almazov National Medical Research Centre
Saint Petersburg, Russia, 197341
Actively Recruiting
Research Team
L
Lyudmila Korostovtseva, MD, PHD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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