Actively Recruiting

Age: 18Years +
All Genders
NCT05865691

Role of Coagulation, Inflammation and Vessels in Chronic Liver Disease

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2024-08-01

360

Participants Needed

1

Research Sites

642 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Chronic liver diseases represent a major public health problem and are responsible for more than 150,000 deaths in Europe each year. These diseases are accompanied by symptoms that profoundly alter the quality of life and mainly affect people of working age, leading to a major economic impact. Coagulation disorders, inflammation and vascular alterations are associated with chronic liver diseases but their role in the onset and/or progression of liver diseases is still not fully understood. A better understanding of chronic liver diseases and in particular of the factors that play a role in the onset and progression of these diseases would improve patient management and therefore have a positive impact on individuals, but also on the healthcare system and the economy.

CONDITIONS

Official Title

Role of Coagulation, Inflammation and Vessels in Chronic Liver Disease

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years or older
  • Patients affiliated with a social security plan or entitled to benefits
  • Patients with chronic liver disease or cirrhosis diagnosed by liver biopsy, liver elastography showing liver stiffness over 10 kPa, or clinical, biological, and imaging criteria indicating chronic liver disease
  • Control participants aged 18 years or older without known liver disease who have had blood drawn before surgery as part of hospital care
Not Eligible

You will not qualify if you...

  • Pregnant or lactating women
  • Persons under guardianship, curatorship, or legal protection
  • Patients under AME (medical aid for foreigners)
  • Patients who have not signed a consent form
  • Recent surgery within 2 weeks before blood test
  • Blood product transfusion within 2 weeks before blood test
  • Use of medication interfering with blood clotting
  • Active extra-hepatic cancer or cancer diagnosed less than 5 years ago
  • Organ transplant recipients (liver, kidney, lung, heart)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Beaujon Hospital

Clichy, France

Actively Recruiting

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Research Team

P

Pierre Emmanuel Rautou

CONTACT

A

Alix Riescher-Tuczkiewicz

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

6

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