Actively Recruiting
The Role of ctDNA Testing Plus AI-based Pathology in Resectable LSCC
Led by Second Xiangya Hospital of Central South University · Updated on 2023-03-21
50
Participants Needed
1
Research Sites
339 weeks
Total Duration
On this page
Sponsors
S
Second Xiangya Hospital of Central South University
Lead Sponsor
S
Shanghai OrigiMed Co., Ltd.
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this observational study is to explore whether ctDNA dynamic monitoring plus AI-based pathology can more effectively predict the therapeutic effect of neoadjuvant chemoimmunotherapy for resectable lung squamous cell carcinoma, so as to accurately guide clinical diagnosis and treatment.
CONDITIONS
Official Title
The Role of ctDNA Testing Plus AI-based Pathology in Resectable LSCC
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histopathology or cytology confirmed lung squamous cell carcinoma
- Age between 18 and 75 years
- Agree to participate and sign informed consent
- Treatment-naive tumor
- Clinical stage II to IIIb resectable or potentially resectable tumor according to AJCC 8th edition
- Sufficient tissue and blood samples available for research
- ECOG performance status score of 0 to 1
You will not qualify if you...
- Unable to understand or cooperate with the study and refuse to sign informed consent
- Non-squamous non-small cell lung cancer
- Unresectable stage IIIa to IIIb tumor
- History of solid organ or blood system transplantation
- Prior treatment with CTLA-4, PD-1, or PD-L1 immune checkpoint inhibitors
- Presence of interstitial lung disease
- Acute or chronic infectious disease
- Pregnant or breastfeeding women
- Participation in other clinical drug trials
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Thoracic Surgery, Second Xiangya Hospital of Central South University, China
Changsha, Hunan, China, 410011
Actively Recruiting
Research Team
Y
Yan Hu, M.D., Ph.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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