Actively Recruiting

Age: 45Years +
All Genders
NCT04666727

Role of Diet on the Microbiome of the Digestive System

Led by M.D. Anderson Cancer Center · Updated on 2025-11-13

30

Participants Needed

1

Research Sites

274 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is to learn more about how diet affects the microbiome (bacteria and microorganisms) of the digestive system. Researchers want to learn if this, in turn, has an effect on if and how people then develop colorectal cancer.

CONDITIONS

Official Title

Role of Diet on the Microbiome of the Digestive System

Who Can Participate

Age: 45Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients presenting for a screening colonoscopy
  • Age 45 years or older
  • Strict vegetarian diet (Group I) or omnivorous diet (Group II) as determined by a diet history questionnaire
  • Non-smoker
  • Ability and willingness to sign informed consent, complete web-based dietary assessment, and provide stool, colonic mucosa, and blood samples
Not Eligible

You will not qualify if you...

  • Current smokers (nicotine abuse only)
  • Positive family history of colon cancer or related syndromes
  • Recent antibiotic use within 1 month
  • History of inflammatory bowel disease, radiation enteritis, or colitis
  • Pregnant or breastfeeding women
  • Women of child-bearing potential with positive pregnancy test
  • Heavy alcohol use (more than 14 drinks per week)
  • Current use of anti-flatulence medications, probiotics, or fiber supplements
  • Major dietary restrictions or following a special diet
  • Positive fecal test or symptoms related to colon disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

M D Anderson Cancer Center

Houston, Texas, United States, 77090

Actively Recruiting

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Research Team

A

Anusha Thomas, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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