Actively Recruiting
Study of Doppler Echoflowmetry to Identify Risk Factors for Complications in Twin Pregnancies A Retrospective and Prospective Observational Study
Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-01-20
6600
Participants Needed
1
Research Sites
307 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying twin pregnancies to see if following different guidelines and more regular monitoring over time has improved how these pregnancies are managed, reducing complications. The study focuses on understanding how carrying twins affects pregnancy outcomes and aims to provide better information for counseling patients. This research includes both past and current patients monitored at a specialized center for complicated pregnancies. Participants with twin pregnancies who were monitored and delivered at a specific hospital will be included. Standard ultrasound checks are done every two weeks for monochorionic twins or monthly for bicorionic twins until 2026. Additional assessments include using an ultrasound device called USCOM 1A to measure maternal blood flow and evaluating the peak pulsatility of the mother's eye artery to predict risks like preeclampsia. Fetal heart function will also be examined using a special echocardiographic technique called STRAIN, which helps detect heart muscle problems. Throughout the study, participants will undergo regular ultrasounds and heart function tests as part of their care. Researchers will collect information about pregnancy complications and monitor both mother and fetus using imaging and blood flow measurements. The main outcome measured is how carrying twins affects the blood flow and heart function of both mother and fetus, with follow-up continuing for up to 100 weeks.
CONDITIONS
Official Title
Role of Doppler Echoflowmetry to Define Risk Factors for the Development of Complications in Twin Pregnancies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age > 18 years
- Twin pregnancy
- Ultrasound monitoring and delivery at Policlinico S Orsola in Bologna, Italy
- Written informed consent form obtained from the patient
You will not qualify if you...
- Delivery completed at another facility
- Desire to undertake voluntary interruption of pregnancy
- Refusal to undergo instrumental monitoring and follow-up at the study center
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Trial Site Locations
Total: 1 location
1
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Bologna, Italy, 40138
Actively Recruiting
Research Team
G
Gianluigi Pilu, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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