Actively Recruiting
Role of Echocardiography and Ultrasound Indices in Resuscitation of Septic Shock Patients
Led by Ain Shams University · Updated on 2026-04-24
40
Participants Needed
1
Research Sites
27 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Fluid replacement is considered the cornerstone of hemodynamic management in critically ill patients especially in patients with septic shock. However, only about 50% of critically ill hemodynamically unstable patients are responsive to fluids. Consequently, the resuscitation of critically ill patients requires an accurate assessment of the patients' intravascular volume status and their volume responsiveness. In this study, we will compare the efficacy of carotid artery flow to echo left ventricular end diastolic volume as a predictive value for fluid resuscitation in septic shock patients.
CONDITIONS
Official Title
Role of Echocardiography and Ultrasound Indices in Resuscitation of Septic Shock Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 50 years old
- Both males and females
- Diagnosed with septic shock according to a SOFA score of 1 or higher
- Presence of at least one sign of acute circulatory failure such as low blood pressure (mean arterial pressure <65 mmHg or systolic <90 mmHg), heart rate over 120 bpm without other cause, low urine output (<1 ml/kg in last hour), high blood lactate (>2 mmol/l) without other cause, or prolonged capillary refill time over 2 seconds
You will not qualify if you...
- Known significant valvular heart disease such as severe aortic insufficiency or stenosis
- Known carotid artery stenosis over 50% or previous carotid surgery
- Contraindications to carotid artery Doppler including wounds, infections, or occlusions of carotid artery
- Arrhythmias that affect stroke volume assessment such as atrial fibrillation or frequent premature ventricular contractions
- Dilated cardiomyopathy
- Poor transthoracic echocardiographic window
- Patient refusal
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Faculty of medicine, Ain Shams University
Cairo, Egypt
Actively Recruiting
Research Team
B
baheya kamel
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here