Actively Recruiting
Role of Elevated Lactate Levels on Lipid and Carbohydrate Metabolism.
Led by Ricardo Mora · Updated on 2026-02-23
24
Participants Needed
1
Research Sites
140 weeks
Total Duration
On this page
Sponsors
R
Ricardo Mora
Lead Sponsor
U
University of Castilla-La Mancha
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to investigate whether the elevated circulating lactate levels of individuals with metabolic syndrome are responsible for their reduced lipolysis and glucose tolerance. The investigators will conduct an intervention study in which blood lactate levels will be elevated via intravenous infusion of sodium lactate. State of the art metabolic assessment using stable isotopes and indirect calorimetry will be used to study alterations in fat and carbohydrate metabolism.
CONDITIONS
Official Title
Role of Elevated Lactate Levels on Lipid and Carbohydrate Metabolism.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women
- Older than 18 years of age
- Women who are not pregnant or are taking contraceptive medication
- Physically active according to WHO guidelines
- Diagnosed with metabolic syndrome by IDF 2009 criteria
- Able to give written and verbal consent to participate
You will not qualify if you...
- Having a chronic illness that prevents exercise
- Blood samples affected at screening as assessed by the principal investigator
- Considered unsuitable for the study by the principal investigator
AI-Screening
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Trial Site Locations
Total: 1 location
1
Facultad de Ciencias del Deporte
San Javier, Murcia, Spain, 30720
Actively Recruiting
Research Team
R
Ricardo MORA RODRIGUEZ, PhD
CONTACT
J
Jesus Garcia-Pallares, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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