Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07387432

Role of Exercise in PRISm and Subsequent Development of COPD

Led by The University of Hong Kong · Updated on 2026-03-06

90

Participants Needed

1

Research Sites

128 weeks

Total Duration

On this page

Sponsors

T

The University of Hong Kong

Lead Sponsor

Q

Queen Mary Hospital, Hong Kong

Collaborating Sponsor

AI-Summary

What this Trial Is About

Preserved Ratio Impaired Spirometry (PRISm) describes individual with spirometry findings of forced expiratory volume (FEV1) and forced vital capacity (FVC) ratio greater than 0.7 but with the FEV1 less than 80% predicted. While the spirometry findings of individuals with PRISm can be transited into obstructive pattern, remains at PRISm or become normal spirometry, limited evidence is on the role of exercise in the course of PRISm. This study aims to investigate the role of exercise, namely exercise with telehealth and walking exercise, together with smoking cessation advice, would alter the clinical course of PRISm.

CONDITIONS

Official Title

Role of Exercise in PRISm and Subsequent Development of COPD

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 or above
  • Smoker or ex-smoker
  • Spirometry shows PRISm with FEV1/FVC ratio greater than or equal to 0.7 and FEV1 less than 80% predicted
  • Able to walk without assistance
  • Able to give informed consent
Not Eligible

You will not qualify if you...

  • Age below 18
  • Non-smoker
  • Spirometry does not show PRISm or unable to perform spirometry
  • Requires assistance to walk
  • Unable to give informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The University of Hong Kong, Queen Mary Hospital

Hong Kong, China

Actively Recruiting

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Research Team

K

King Pui Florence Chan, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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