Actively Recruiting
Role of Menopause in Thermoregulation
Led by Penn State University · Updated on 2026-04-06
24
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at increased risk for adverse events. Previous heat waves report that women over 65 experience worse health outcomes than any other age group and age matched men. Aging and reproductive hormones, specifically estrogen, independently alter responses to heat stress. However, the combined effects of low estrogen following menopause and aging on the response to heat stress are unknown. In this study, the investigators will identify the role of estrogen in pre and post menopausal women on thermoregulatory responses to heat stress.
CONDITIONS
Official Title
Role of Menopause in Thermoregulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women ages 42 to 64
You will not qualify if you...
- Crohn's disease, diverticulitis, or similar gastrointestinal disease
- Abnormal resting exercise electrocardiogram (ECG)
- Tobacco use
- High-risk determined by the Atherosclerotic Cardiovascular Disease (CVD) Risk Factor Assessment
- Using hormone therapy
- Using hormonal contraceptives
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Noll Laboratory
University Park, Pennsylvania, United States, 16802
Actively Recruiting
Research Team
W
W. Larry Kenney, Ph.D.
CONTACT
O
Olivia K. Leach, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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