Actively Recruiting
The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic Cancer
Led by Nuvance Health · Updated on 2026-04-13
200
Participants Needed
1
Research Sites
782 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Aberrant miRNA production has been linked to a wide range of human cancers and shown to play important roles in their genesis and growth. These miRNA can be detected in the blood and tumors of patients with cancer. The investigators hypothesize that the detection of certain miRNAs present in the blood/serum of patients with pancreatic cancer may be important to the early diagnosis of the disease. Furthermore, the investigators hypothesize that miRNA detection in PC patients will yield prognostic information and help predict the response to treatment.
CONDITIONS
Official Title
The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Biopsy-proven adenocarcinoma of the pancreas
- Initially inoperable disease, either locally advanced or metastatic
- Recurrent disease after Whipple procedure allowed
- Patients able to undergo surgery after neoadjuvant therapy will continue follow-up
- Radiographically measurable disease
- ECOG performance status of 2 or less
- Willingness to provide required information and specimens
- Signed written consent to participate
You will not qualify if you...
- Prior anti-cancer treatments for metastatic pancreatic cancer
- Receiving systemic therapy for another cancer except controlled prostate cancer under androgen deprivation therapy
- Presence of other active cancers except adequately treated local skin cancers, cervical carcinoma in situ, superficial bladder cancer, asymptomatic prostate cancer under control, other stage 1 or 2 cancers in complete remission, or any cancer in complete remission for more than 5 years
AI-Screening
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Trial Site Locations
Total: 1 location
1
Nuvance Health
Norwalk, Connecticut, United States, 06856
Actively Recruiting
Research Team
P
Pramila Krumholtz, RN
CONTACT
T
Tammy Lo, MSN
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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