Actively Recruiting

Age: 18Years +
FEMALE
NCT06877065

Role of MRI Assessment in Fertility Sparing Treatment for Cervical Cancer at Staging and Follow-up and for Identification of Risk Factors for Aggressive Disease.

Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2025-03-14

60

Participants Needed

1

Research Sites

252 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to investigate the role of MRI, including DWI, in the staging and evaluation of response to fertility sparing treatment, including both primary surgery Protocol FeST-CC V.1.0 of November 10, 2023 Pag. 5 \| 23 (RT or CKC) or after NACT, followed by CKC, in patients with ECC (FIGO 2018 stage IB1- IIA1), desiring to preserve their fertility.

CONDITIONS

Official Title

Role of MRI Assessment in Fertility Sparing Treatment for Cervical Cancer at Staging and Follow-up and for Identification of Risk Factors for Aggressive Disease.

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with cervical cancer FIGO stage up to IB2-IIA1 (tumor size < 4 cm) wishing to preserve fertility treated at the Oncological Gynecology Unit of Foundation Policlinico Universitario Agostino Gemelli
  • Absence of nodal disease
  • No menopausal status
  • Wish to preserve fertility
  • Refusal of radical treatment
  • Patients who had pre-treatment and post-treatment magnetic resonance imaging
  • Availability of digital MR images and histopathological samples
Not Eligible

You will not qualify if you...

  • Patients aged under 18 years
  • Neuroendocrine cervical tumors or other rare histology such as glassy cells or clear cell carcinoma non-HPV related adenocarcinoma
  • Ongoing pregnancy at the time of diagnosis
  • Patients without available MR images on digital media or with low quality images

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Advanced Radiology Center- Fondazione Policlinico Universitario A. Gemelli IRCCS

Rome, Italy, 00168

Actively Recruiting

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Research Team

B

Benedetta Gui

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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