Actively Recruiting
The Role of Proprioceptive Deficits, Psychosocial Factors and Inflammation in Pregnancy-related Pelvic Girdle Pain
Led by Hasselt University · Updated on 2026-03-03
192
Participants Needed
1
Research Sites
434 weeks
Total Duration
On this page
Sponsors
H
Hasselt University
Lead Sponsor
Z
Ziekenhuis Oost-Limburg
Collaborating Sponsor
AI-Summary
What this Trial Is About
A large proportion of pregnant women develop pregnancy-related low back and/or pelvic girdle pain (PPGP), which often does not recover spontaneously postpartum. As a result, 10% of women with PPGP are thus crucial. However, the underlying mechanisms of PPGP are still poorly understood. The main objective of this study is to investigate whether lumbar proprioceptive deficits, a disturbed body perception at the lumbar spine, psychosocial factors (incl. pain-related fear of movement, depression, anxiety and stress) and increased serum concentrations of specific inflammatory mediators are associated with (1) a reduced postural control and (2) the development and/or persistence of PPGP in multiparous women during the first and third trimester of pregnancy, and six weeks and six months postpartum.
CONDITIONS
Official Title
The Role of Proprioceptive Deficits, Psychosocial Factors and Inflammation in Pregnancy-related Pelvic Girdle Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Singleton pregnancy
- Pregnant with second or subsequent child
- No current pregnancy-related pelvic girdle pain (PPGP) during this pregnancy
- Willing to provide written informed consent
- Age- and BMI-matched nulliparous women willing to provide written informed consent
You will not qualify if you...
- Pregnancy beyond 16 weeks gestation
- Current or previous PPGP during this pregnancy
- History of surgery or major trauma to the spine or pelvis
- Surgery or trauma to lower limbs less than two years ago
- Surgery or trauma to lower limbs more than two years ago with ongoing symptoms like pain or stiffness
- Specific balance or vestibular disorders
- Rheumatic condition diagnosis or treatment
- Neurological abnormalities such as peripheral neuropathy
- Uncorrected visual problems
- Acute ankle problems
- Absolute or relative bed rest due to pregnancy complications
- Formal diagnosis of psychiatric disorder
- Non-Dutch speaking
- Low back or pelvic girdle pain within six months before inclusion (for nulliparous women)
- History of chronic low back or pelvic girdle pain (for nulliparous women)
- Spinal deformities (for nulliparous women)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hasselt University
Hasselt, Belgium, 3590
Actively Recruiting
Research Team
N
Nina Goossens, PhD, PT
CONTACT
L
Lotte Janssens, PhD, PT
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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