Actively Recruiting
Role of Regional Lung Compliance and Dynamic Transpulmonary Driving Pressure in the Liberation Difficulty in Tracheostomized Patients Receiving Prolonged Mechanical Ventilation
Led by National Taiwan University Hospital · Updated on 2025-06-04
120
Participants Needed
1
Research Sites
180 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This project focuses on the analysis of the correlation between transpulmonary driving pressure and uneven lung ventilation and regional lung compliance in patients using prolonged mechanical ventilation (PMV), in order to understand the clinical occurrence of failure of the final spontaneous breathing test and inability to breathe. Respiratory physiology impairments in patients successfully discharged from respirators.
CONDITIONS
Official Title
Role of Regional Lung Compliance and Dynamic Transpulmonary Driving Pressure in the Liberation Difficulty in Tracheostomized Patients Receiving Prolonged Mechanical Ventilation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Post-tracheostomy patients transferred to the subacute respiratory care ward who have used respirators for at least 14 days
- At least 20 years old
- Oxygen concentration needed on the respirator does not exceed 50%
You will not qualify if you...
- Unstable vital signs or need for continuous vasopressors
- Pregnancy
- Chronic obstructive pulmonary disease or asthma
- Contraindications to esophageal pressure balloon placement such as abnormal blood clotting, esophageal varices, or recent esophageal/gastric surgery within 6 months
- Contraindications to electrical impedance tomography such as having a heart rhythm regulator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Taiwan University Hospital
Taipei, Taiwan
Actively Recruiting
Research Team
J
Jih-Shuin Jerng, MD, PhD, Principal Investigator
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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