Actively Recruiting
Role of Sleep Reactivity in Shift Work Disorder
Led by Henry Ford Health System · Updated on 2025-10-14
150
Participants Needed
1
Research Sites
247 weeks
Total Duration
On this page
Sponsors
H
Henry Ford Health System
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this project is to test sleep reactivity as an independent cause of Shift Work Disorder (SWD). The primary hypothesis is that those with high sleep reactivity will show persistent SWD symptoms after experimental reduction of circadian misalignment, which will then be mitigated with CBT.
CONDITIONS
Official Title
Role of Sleep Reactivity in Shift Work Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must be working a fixed nightshift schedule, defined as working at least three night shifts a week
- Night shifts must begin between 6:00 PM and 2:00 AM and last between 8 to 12 hours
- Participants must plan to maintain their nightshift schedule for the entire study duration
- Participants must have Shift Work Disorder diagnosed based on ICSD-3 criteria
- Participants must show circadian misalignment with a baseline melatonin onset between 6:00 PM and 1:00 AM
- Participants must be at least 18 years old
You will not qualify if you...
- Insomnia disorder or excessive sleepiness that started before beginning shift work
- Stopping the nightshift schedule during the study
- Presence of other sleep disorders such as obstructive sleep apnea or narcolepsy confirmed by clinical tests
- Diagnosis of bipolar disorder
- History of neurological disorders based on self-report and medical history
- Pregnancy
- Alcohol use disorder
- Illicit drug use detected by self-report or urine drug screen if suspected
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Henry Ford Columbus Medical Center
Novi, Michigan, United States, 48377
Actively Recruiting
Research Team
P
Philip Cheng, PhD
CONTACT
M
Marleigh Treger, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
OTHER
Number of Arms
4
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