Actively Recruiting

Phase 4
Age: 18Years - 60Years
All Genders
NCT07098780

Role of Tranexamic Acid in Reducing Hemorrhagic Events in Bariatric Surgery

Led by Patel Hospital, Pakistan · Updated on 2025-08-01

140

Participants Needed

1

Research Sites

115 weeks

Total Duration

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AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if tranexamic acid (TXA) helps reduce bleeding during bariatric surgery, such as laparoscopic sleeve gastrectomy (LSG) and mini gastric bypass (MGB). It will also look at how safe TXA is for people undergoing these procedures. The main questions it aims to answer are: Does TXA reduce the amount of blood loss during bariatric surgery? Are there any side effects or complications in patients who receive TXA? Researchers will compare TXA to standard care (no TXA) to see if it is effective in reducing bleeding. Participants will: Receive either TXA or no TXA (placebo) before surgery Undergo standard bariatric surgery (LSG or MGB) Have their blood loss, hemoglobin levels, and any complications monitored during and after surgery

CONDITIONS

Official Title

Role of Tranexamic Acid in Reducing Hemorrhagic Events in Bariatric Surgery

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients above 18 years of age
  • Undergoing Laparoscopic Sleeve Gastrectomy and Mini Gastric Bypass (MGB)
  • Diagnosed with morbid obesity
Not Eligible

You will not qualify if you...

  • Taking anti-platelet or anti-coagulant medications
  • Having inherited or acquired bleeding disorders
  • Having any acute medical condition that increases bleeding risk
  • Using hormonal contraceptives
  • Known allergy to tranexamic acid (TXA)
  • Using female hormonal replacement therapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Patel Hospital

Karachi, Sindh, Pakistan, 75300

Actively Recruiting

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Research Team

Y

Yusra Jamshed, MBBS

CONTACT

U

Umama Ehtisham, MBBS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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