Actively Recruiting

Age: 18Years +
All Genders
NCT07018037

Role of TTV During First-line Immunotherapy Treatment in Patients With Renal Cell Carcinoma

Led by Regina Elena Cancer Institute · Updated on 2025-06-12

20

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this project is to descriptively explore the trend of torquetenovirus viral load TTV during therapy with immune checkpoint inhibitor ICI in these patients, to evaluate a possible role of this virus as a biomarker of response.

CONDITIONS

Official Title

Role of TTV During First-line Immunotherapy Treatment in Patients With Renal Cell Carcinoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients over 18 years of age
  • Histological diagnosis of clear cell renal cell carcinoma
  • Evidence of advanced or metastatic disease
  • Patients diagnosed with metastatic clear cell renal cell carcinoma about to start first-line immunotherapy (ICI + ICI or ICI + TKI)
  • Patients able to comply with the study procedures
  • Patients who give written informed consent personally or through a witness before starting any study procedure
Not Eligible

You will not qualify if you...

  • Previous neoplasms
  • Previous antineoplastic treatments
  • Previous steroid treatments
  • Active viral infections such as HCV or HIV
  • Lack of autonomy in adhering to study procedures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

"Regina Elena" National Cancer Institute

Rome, Italy, 00144

Actively Recruiting

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Research Team

F

Fabio Calabrò, Doctor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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