Studying Ultrasound Patterns to Detect Fetal Brain Malformations During Pregnancy

What this Trial Is About

This research aims to explore the relationship between new ultrasound imaging patterns and malformations of the fetal central nervous system CNS. It focuses on understanding brain development during pregnancy by analyzing ultrasound scans, seeking to identify clearer patterns that may improve the diagnosis of fetal brain abnormalities. The study compares ultrasound images from fetuses diagnosed with CNS malformations to those from healthy fetuses, helping to better characterize these malformations. The study involves reviewing ultrasound images routinely taken during pregnancy for two groups fetuses with CNS malformations and healthy fetuses without such abnormalities. Data collected includes maternal age, pregnancy history, conception method, family history, type and timing of CNS malformation diagnosis, pregnancy outcomes, and newborn health measures such as sex, weight, and neurological assessment shortly after birth. Participants will provide information about their pregnancies and allow access to ultrasound images previously obtained. Researchers will assess correlations between ultrasound patterns and fetal CNS malformations as the main outcome. Additional comparisons between affected and healthy fetuses are planned. The study spans up to 100 weeks, including prenatal imaging review and postnatal newborn assessments, with ongoing monitoring of pregnancy outcomes and neurological health.

The Role of Ultrasonography in Pregnancy in the Study of Fetal Central Nervous System Malformations