Actively Recruiting
Role of Urinary Sphingosine 1-Phosphate as a Biomarker for Detrusor Hyperactivity in Multiple Sclerosis
Led by University Hospital, Toulouse · Updated on 2025-12-31
400
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to establish a link between urinary Sphingosine 1-Phosphate (S1P) levels and detrusor activity in multiple sclerosis (MS) patients. MS often involves urological symptoms, primarily overactive bladder. The gold standard for evaluation and treatment monitoring is invasive urodynamic testing. Preliminary research at Toulouse University Hospital suggests urinary S1P levels may be a potential biomarker for detrusor activity in MS. This study aims to confirm this potential biomarker's utility.
CONDITIONS
Official Title
Role of Urinary Sphingosine 1-Phosphate as a Biomarker for Detrusor Hyperactivity in Multiple Sclerosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- French residents enrolled in the social security system
- Diagnosed with multiple sclerosis according to McDonald 2017 criteria
- Scheduled for urodynamic assessment as part of their management
You will not qualify if you...
- Pregnant or lactating females
- Patients under legal guardianship
- Untreated urinary tract infection at the time of inclusion
- Known anatomical subvesical obstruction
- Known pelvic floor disorder
- Urothelial carcinoma
- Interstitial cystitis
- Augmentation cystoplasty
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Toulouse Hospital
Toulouse, France
Actively Recruiting
Research Team
X
Xavier Game, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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