Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07201649

Roles of Hepatic Insufficiency, Hepatic Fibrosis, and Inorganic Pyrophosphate in the Progression of Arterial Calcifications

Led by Centre Hospitalier Universitaire de Nice · Updated on 2025-12-01

95

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Individuals with metabolic syndrome (MetS), particularly those with type 2 diabetes (T2D), and/or metabolic dysfunction-associated steatohepatitis or MASH face an elevated risk of major cardiovascular events (MACE). We showed decrease plams level of PPi in patients with liver cirrhosis. We hypothezised that liver transplant should block AC and restore PPi plasma level.

CONDITIONS

Official Title

Roles of Hepatic Insufficiency, Hepatic Fibrosis, and Inorganic Pyrophosphate in the Progression of Arterial Calcifications

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients requiring liver transplantation for chronic liver disease
Not Eligible

You will not qualify if you...

  • MELD score greater than 25
  • Presence of viral replication

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
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+1

Trial Site Locations

Total: 1 location

1

CHU de Nice

Nice, Alpes-maritimes, France, 06200

Actively Recruiting

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Research Team

G

Guillaume FAVRE, PhD

CONTACT

G

Gullaume Marrane

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Roles of Hepatic Insufficiency, Hepatic Fibrosis, and Inorganic Pyrophosphate in the Progression of Arterial Calcifications | DecenTrialz