Actively Recruiting

Age: 18Years +
All Genders
NCT07425639

ROLL'YN-OMA: an Observational Study in Patients Treated by Omlyclo®, an Omalizumab Biosimilar

Led by Celltrion HealthCare France · Updated on 2026-02-23

225

Participants Needed

1

Research Sites

152 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

ROLL'YN-OMA is a real-world study in patients receiving standard biologic therapies who have been in control and/or remission of their disease for at least 3 months and whose physician has independently decided, within the framework of a shared medical decision, to switch them to OMLYCLO®. The primary objective of this study is to evaluate the maintenance of this control and/or clinical remission 12 months after initiation of the biosimilar, and subsequently, patient satisfaction at 6 and 12 months.

CONDITIONS

Official Title

ROLL'YN-OMA: an Observational Study in Patients Treated by Omlyclo®, an Omalizumab Biosimilar

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older diagnosed with severe asthma or chronic spontaneous urticaria
  • Treated with reference omalizumab for at least 6 months prior to inclusion
  • Stable disease or in clinical remission for at least 3 months, as assessed by disease-specific activity scores
  • Physician has decided to switch to OMLYCLO4 biosimilar on the day of inclusion
  • Able to start biosimilar treatment within 60 days of inclusion
  • Have an email address and mobile phone number
  • Able to understand and complete questionnaires in French
  • Agree to participate in the study
  • Affiliated with or beneficiary of a French Social Security scheme
Not Eligible

You will not qualify if you...

  • Under guardianship, trusteeship, or deprived of liberty
  • Pregnant or women of childbearing potential wishing to become pregnant during treatment
  • Currently participating in another clinical trial prohibiting simultaneous study participation
  • Contraindicated to the study products

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU Montpellier

Montpellier, France

Actively Recruiting

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Research Team

S

Salim BENKHALIFA, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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