Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07518004

ROME GS System Study

Led by Senseonics, Inc. · Updated on 2026-04-21

60

Participants Needed

4

Research Sites

146 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this clinical investigation is to demonstrate that the proposed physical changes to the ROME GS Sensor do not have any adverse impact on safety and performance when compared to the Eversense 365 Sensor.

CONDITIONS

Official Title

ROME GS System Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Clinical diagnosis of diabetes mellitus for at least 1 year
  • Signed informed consent form and willingness to follow study requirements
Not Eligible

You will not qualify if you...

  • History of unexplained severe hypoglycemia causing loss of consciousness or seizures within 6 months
  • History of diabetic ketoacidosis requiring emergency or hospital visit within 6 months
  • Diagnosis of gastroparesis
  • Female of childbearing potential who is pregnant, lactating, intends to become pregnant, or not using birth control
  • Conditions preventing sensor placement, operation, removal, or transmitter use, including arm deformities or skin issues
  • Symptomatic coronary artery disease, unstable angina, recent heart attack, stroke, uncontrolled high blood pressure, heart failure, or cardiac arrhythmia (except benign PACs/PVCs)
  • Hematocrit less than 38% or greater than 60% at screening
  • History of hepatitis B, hepatitis C, or HIV
  • Current seizure disorder treatment without neurologist clearance
  • History of adrenal insufficiency
  • Current or likely need for immunosuppressants, chemotherapy, anticoagulants (except aspirin), topical glucocorticoids over sensor site only, or antibiotics for chronic infection
  • Need or likely need for MRI
  • Known allergy to topical/local anesthetics or glucocorticoids
  • Any condition making participation unsafe or not in best interest, including psychiatric conditions or substance abuse
  • Participation in another drug or device clinical trial within 2 weeks prior or intention during study
  • Presence of active implanted devices (e.g., implantable defibrillator); passive devices allowed
  • Use of FDA-approved Eversense CGM System not provided by study is not allowed

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Headlands Research - AMCR Institute

Escondido, California, United States, 92025

Actively Recruiting

2

Flourish Research - Diablo Clinical Research

Walnut Creek, California, United States, 94598

Not Yet Recruiting

3

Flourish Research - San Antonio

San Antonio, Texas, United States, 78229

Actively Recruiting

4

Rainier Clinical Research Center

Renton, Washington, United States, 98057

Actively Recruiting

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Research Team

M

Maggie Lewis

CONTACT

S

Susan Huynh

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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ROME GS System Study | DecenTrialz