Actively Recruiting

Age: 18Years +
All Genders
NCT06743035

Ropeginterferon Alfa-2b in Patients With Polycythemia Vera (PV) Without Symptomatic Splenomegaly

Led by iOMEDICO AG · Updated on 2026-01-09

200

Participants Needed

1

Research Sites

238 weeks

Total Duration

On this page

Sponsors

I

iOMEDICO AG

Lead Sponsor

A

AOP Orphan Pharmaceuticals Germany GmbH

Collaborating Sponsor

AI-Summary

What this Trial Is About

The primary objective of this non interventional study is to evaluate symptom burden in adult patients with PV without symptomatic splenomegaly during treatment with ropeginterferon alfa-2b in a real-world setting. Further patient-relevant endpoints include effectiveness including complete hematologic response (CHR), event-free survival (EFS), safety and tolerability, treatment reality including dosing details as well as factors affecting treatment decision making.

CONDITIONS

Official Title

Ropeginterferon Alfa-2b in Patients With Polycythemia Vera (PV) Without Symptomatic Splenomegaly

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 2 years or older
  • Confirmed diagnosis of polycythemia vera without symptomatic splenomegaly
  • Indicated for treatment with ropeginterferon alfa-2b according to current product guidelines
  • No prior treatment with ropeginterferon alfa-2b, but enrollment allowed up to 6 weeks after first dose if still on treatment
  • Signed informed consent form dated
  • Willingness to participate in German-language patient-reported outcome assessments and complete questionnaires at enrollment
  • Other criteria as per current product guidelines
Not Eligible

You will not qualify if you...

  • Participation in another interventional clinical trial (except follow-up studies)
  • Any contraindications listed in the current product guidelines for ropeginterferon alfa-2b

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Onkologisches Studienzentrum Dr. med. Ingo Zander & Dr. med. Eyck von der Heyde

Hanover, Lower Saxony, Germany, 30161

Actively Recruiting

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Research Team

L

Laura Serrer

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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