Actively Recruiting
ROTEM in Sepsis Trauma Outcome in Intensive Care
Led by Region Stockholm · Updated on 2025-03-24
600
Participants Needed
1
Research Sites
112 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective observational study aims to investigate the ability of advanced ROTEM analysis using Principal Component Analysis (PCA) to detect early signs of disseminated intravascular coagulation (DIC) and trauma-induced coagulopathy (TIC) in hospitalized patients with sepsis or trauma. Standard coagulation tests and ROTEM measurements will be collected and analyzed in relation to clinical outcomes.
CONDITIONS
Official Title
ROTEM in Sepsis Trauma Outcome in Intensive Care
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Trauma alarm activated at hospital admission
- New Injury Severity Score (NISS) greater than 15
- Transfer to hospital within 7 days of trauma with NISS greater than 15
- Meeting Sepsis-3 criteria for sepsis
- Receipt of intravenous beta-lactam or aminoglycoside antibiotics within 48 hours of admission for sepsis patients
- Patients undergoing elective surgery without expected coagulopathy
You will not qualify if you...
- Isolated chronic subdural hematoma in trauma patients
- No underlying traumatic event despite trauma alarm
- Age under 18 years for trauma and sepsis patients
- Ongoing anticoagulant treatment for control patients
- Life-threatening illness classified as ASA IV-V for control patients
- Age under 18 years for control patients
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Region Stockholm
Stockholm, Sweden
Actively Recruiting
Research Team
M
Mattias Günther, MD PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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