Actively Recruiting
Routine Use of Negative Pressure Wound Therapy in Primary Hip and Knee Arthroplasties; a Randomized Controlled Trial
Led by Chinese University of Hong Kong · Updated on 2023-12-29
82
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the use of negative pressure wound therapy (NPWT) for patients undergoing total knee and total hip arthroplasty. This study aims to compare the number of wound complications within 21 days after surgery and assess the appearance and quality of scarring. The trial is randomized and includes 40 patients to help understand how NPWT affects healing in these procedures. Participants will be randomly assigned to one of two groups. Both groups will receive layered wound closure using specific sutures and fixation strips. The experimental group will have the Smith & Nephew PICO dressing with a small suction pump to apply negative pressure, designed to be comfortable and not interfere with mobility. The control group will receive the same dressing without suction. This setup allows evaluation of the effect of negative pressure on wound healing. During the study, researchers will monitor wound-related complications and use patient and observer scales, including the Patient Scale and Observer Scale (POSAS) and a multi-category visual analogue scale, all assessed 21 days after surgery. Participants will be observed for the first three weeks post-surgery to record wound issues and scar quality. The total participation duration and follow-up focus on early outcomes after joint arthroplasty.
CONDITIONS
Brief Title
Routine Use of Negative Pressure Wound Therapy THR TKR RCT
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing total knee or total hip arthroplasty at Prince of Wales Hospital, Hong Kong.
- Age 50 years or older.
You will not qualify if you...
- Use of steroids or other immune modulators known to affect wound healing.
- Prior surgery to the knee or hip.
- Skin conditions such as eczema that may impair healing or lead to widened scars.
- Known history of hypertrophic scarring or keloid formation.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo surgery for total knee or total hip arthroplasty with layered wound closure and receive either negative pressure wound therapy dressing or standard dressing.
1 visit (in-person)
Duration - 21 days after surgery
Participants are monitored for wound-related complications and assessed using patient and observer scar scales and visual analogue scales.
Approximately 3 visits (in-person) during the 21 days
Trial Site Locations
Total: 1 location
1
The Chinese University of Hong Kong
Hong Kong, Hong Kong
Actively Recruiting
Research Team
M
Michael Tim-Yun Ong
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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