Actively Recruiting
Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients
Led by Mansoura University · Updated on 2025-05-13
46
Participants Needed
1
Research Sites
28 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients with kidney failure who require hemodialysis often suffer from anemia (low red blood cell count), heart and blood vessel problems, and a condition involving poor nutrition, inflammation, and hardening of the arteries (called MIA syndrome). Standard treatments for anemia often involve injections and iron supplements. This study aims to see if a newer oral medication, Roxadustat, works better than these standard treatments not only for anemia but also for improving cardiovascular health and the MIA syndrome. Participants in the study will be randomly assigned (like by chance) to one of two groups. One group will receive Roxadustat, while the other group will continue with their conventional anemia treatment. Researchers will compare the effects on heart function, markers of nutrition and inflammation, and anemia levels in both groups over a 6-month period.
CONDITIONS
Official Title
Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age of patient is more than 18.
- Patients who are willing to sign informed consent.
- Patients with end-stage kidney disease on chronic hemodialysis for more than 3 months.
You will not qualify if you...
- Current pregnancy or lactation.
- Patients with pre-existing malignancy.
- Patients with psychosis or on hypnotic medications.
- Patients who refuse to participate in the study.
- Known history of blood disorders or anemia causes other than chronic kidney disease or dialysis.
- Patients with severe cardiovascular disease.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Urology and Nephrology Center, Mansoura University
Al Mansurah, Dakahliya, Egypt, 35111
Actively Recruiting
Research Team
I
Ibrahim M Galalah, MSC
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here