Actively Recruiting
RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative
Led by NYU Langone Health · Updated on 2026-04-21
46
Participants Needed
1
Research Sites
46 weeks
Total Duration
On this page
Sponsors
N
NYU Langone Health
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this sham-controlled pilot randomized controlled trial (RCT) is to evaluate the feasibility, safety, and preliminary efficacy of a one-month intervention consisting of 20 home-based active or sham RS-tDCS sessions paired with audio track guided mindfulness meditation practice in otherwise healthy adults seeking to reduce cannabis use in the context of cannabis use disorder (CUD).
CONDITIONS
Official Title
RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 22-65 years (inclusive)
- Currently meet DSM-V criteria for cannabis use disorder
- Positive urine test for cannabis (11-COOH-THC)
- Seeking treatment to reduce or stop cannabis use with Marijuana Ladder score between 5 and 8
- Kessler Psychological Distress Scale (K10) score less than 35
- Wide Range Achievement Test-5 (WRAT-5) score of 85 or higher
- Ability to use mobile devices
- Fluent in English or Spanish
You will not qualify if you...
- Use cannabis only as prescribed by a provider
- Substance use disorder for any psychoactive substance other than cannabis within past 6 months
- Alcohol use disorder within past 6 months
- Primary psychiatric disorder such as major depression, bipolar disorder, or psychotic disorder independent of cannabis use disorder
- Current diagnosis of bipolar disorder, psychotic disorder, or other substance or alcohol use disorder
- Primary neurologic or major medical disorder interfering with study participation
- Enrolled in concurrent individual or group therapy for substance use disorder
- History of moderate or severe traumatic brain injury
- Seizure disorder or seizure history within last 5 years
- Presence of metal or active implants in the head or neck
- Any skin disorder or sensitive skin near stimulation sites
- Pregnant, planning pregnancy, or breastfeeding during the study period
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
NYU Langone Health
New York, New York, United States, 10016
Actively Recruiting
Research Team
S
Shayna Pehel
CONTACT
G
Giuseppina Pilloni
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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