Actively Recruiting

Age: 3Years - 16Years
All Genders
ID04235517

Behaviour of the Growth Plate in Children Undergoing Permanent or Temporary Hemi-epiphysiodesis or Epiphysiodesis Using Radiostereometric Analysis (RSA)

Led by Oslo University Hospital · Updated on 2025-09-04

10

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying how the growth plate behaves in children who have undergone temporary hemi-epiphysiodesis or epiphysiodesis, procedures used to treat limb length differences and axial deviations in the lower limbs. This observational study uses radiostereometric analysis (RSA) to accurately measure growth in three dimensions, helping to detect asymmetric growth and determine the best timing for implant removal. The study involves children treated with guided growth for axial deviations or temporary epiphysiodesis for limb length discrepancies. During surgery, small tantalum beads are implanted near the growth plate, allowing precise RSA imaging to monitor growth patterns during and after the procedures. This method offers microscopic accuracy in tracking changes over time. Participants will be monitored over a period of four years to observe growth plate behavior following surgery. The study includes regular follow-up imaging using RSA to measure growth in three planes. Researchers aim to gather detailed data on growth changes to improve treatment timing and outcomes for children with these conditions.

CONDITIONS

Brief Title

RSA Study on the Behaviour of the Growth Plate During and After Temporary Hemi-epiphysiodesis and Epiphysiodesis

Who Can Participate

Age: 3Years - 16Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children with idiopathic axial deviations in the lower extremities
  • Children with limb length discrepancies where timing of epiphysiodesis is difficult due to a large difference between skeletal age and chronological age
  • Aged between 3 and 16 years
Not Eligible

You will not qualify if you...

  • Children with axial deviations and pathological growth plates

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Surgery and Immediate Post-operative Care

Duration - Day of surgery plus initial recovery period

Participants undergo surgery involving implantation of small tantalum beads on either side of the growth plate (physis) and receive immediate post-operative care.

1 surgery visit (in-person) and immediate post-operative care

Post-operative Follow-up

Duration - Up to 4 years

Participants are followed after surgery to monitor the behaviour of the growth plate over time using radiostereometric analysis (RSA).

Multiple follow-up visits for RSA imaging over 4 years

Trial Site Locations

Total: 1 location

1

The Ortopedic dep at Oslo Unversity Hospital, Rikshospitalet

Oslo, Norway, 0424

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Research Team

A

Anne B Breen, MD

J

Joachim Horn, MD,PHD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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