Actively Recruiting
rTMS for Postoperative Brain Tumor Patients
Led by Brian J.Gill · Updated on 2026-04-15
6
Participants Needed
1
Research Sites
95 weeks
Total Duration
On this page
Sponsors
B
Brian J.Gill
Lead Sponsor
C
Columbia University
Collaborating Sponsor
AI-Summary
What this Trial Is About
When doctors perform surgery to remove brain tumors, the goal is to take out as much of the tumor as possible while keeping the patient's brain functions intact. However, sometimes patients have trouble with movements like walking or using their hands after surgery. One reason for this is unintentional damage to important areas of the brain during the operation. A technique called Transcranial Magnetic Stimulation (TMS) might help patients recover these lost abilities faster. The investigators are conducting a study to see if TMS can help patients recover their movement abilities after brain tumor surgery. TMS uses magnetic pulses to stimulate specific parts of the brain. In this study, the investigators will treat six patients with TMS once per day for three days in a row. Three patients with recent movement difficulties one to two weeks after surgery will be recruited for this study; they will also receive physical therapy. An additional three patients with persisting movement difficulties up to three years after tumor surgery will also be recruited for this study, regardless of whether or not they receive physical therapy. The investigators will use two standard tests to see how well patients can move before and after the TMS treatment. These tests will help the investigators understand if TMS is making a difference in their recovery.
CONDITIONS
Official Title
rTMS for Postoperative Brain Tumor Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 22-65 years who have had brain tumor surgery
- Patients may be receiving other therapies except prior TMS therapy
- Patients with motor deficits 1-2 weeks after surgery defined by specific muscle strength scores
- Patients with chronic motor deficits up to 3 years after surgery
- Ability and willingness to provide written informed consent
You will not qualify if you...
- History of seizures
- Presence of implanted devices such as pacemakers or cochlear implants
- Patients who only had a brain biopsy without tumor removal
- Cognitive impairment with Mini Mental State Examination score below 26
- History of bipolar disorder
- Pregnant or breastfeeding individuals
- Active suicidal thoughts or plans
- History of moderate to severe heart disease
- Other neurological conditions causing brain damage like stroke or multiple sclerosis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Columbia University Irving Medical Center
New York, New York, United States, 10032
Actively Recruiting
Research Team
R
Research Nurse Navigator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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