Actively Recruiting

Phase Not Applicable
Age: 22Years - 65Years
All Genders
NCT07530536

rTMS for Postoperative Brain Tumor Patients

Led by Brian J.Gill · Updated on 2026-04-15

6

Participants Needed

1

Research Sites

95 weeks

Total Duration

On this page

Sponsors

B

Brian J.Gill

Lead Sponsor

C

Columbia University

Collaborating Sponsor

AI-Summary

What this Trial Is About

When doctors perform surgery to remove brain tumors, the goal is to take out as much of the tumor as possible while keeping the patient's brain functions intact. However, sometimes patients have trouble with movements like walking or using their hands after surgery. One reason for this is unintentional damage to important areas of the brain during the operation. A technique called Transcranial Magnetic Stimulation (TMS) might help patients recover these lost abilities faster. The investigators are conducting a study to see if TMS can help patients recover their movement abilities after brain tumor surgery. TMS uses magnetic pulses to stimulate specific parts of the brain. In this study, the investigators will treat six patients with TMS once per day for three days in a row. Three patients with recent movement difficulties one to two weeks after surgery will be recruited for this study; they will also receive physical therapy. An additional three patients with persisting movement difficulties up to three years after tumor surgery will also be recruited for this study, regardless of whether or not they receive physical therapy. The investigators will use two standard tests to see how well patients can move before and after the TMS treatment. These tests will help the investigators understand if TMS is making a difference in their recovery.

CONDITIONS

Official Title

rTMS for Postoperative Brain Tumor Patients

Who Can Participate

Age: 22Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 22-65 years who have had brain tumor surgery
  • Patients may be receiving other therapies except prior TMS therapy
  • Patients with motor deficits 1-2 weeks after surgery defined by specific muscle strength scores
  • Patients with chronic motor deficits up to 3 years after surgery
  • Ability and willingness to provide written informed consent
Not Eligible

You will not qualify if you...

  • History of seizures
  • Presence of implanted devices such as pacemakers or cochlear implants
  • Patients who only had a brain biopsy without tumor removal
  • Cognitive impairment with Mini Mental State Examination score below 26
  • History of bipolar disorder
  • Pregnant or breastfeeding individuals
  • Active suicidal thoughts or plans
  • History of moderate to severe heart disease
  • Other neurological conditions causing brain damage like stroke or multiple sclerosis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Columbia University Irving Medical Center

New York, New York, United States, 10032

Actively Recruiting

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Research Team

R

Research Nurse Navigator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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rTMS for Postoperative Brain Tumor Patients | DecenTrialz