Actively Recruiting
RTMS and Steroid Joint Steroid Injection in Chronic Spinal Pain
Led by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Updated on 2025-02-05
40
Participants Needed
2
Research Sites
132 weeks
Total Duration
On this page
Sponsors
L
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lead Sponsor
W
Western University, Canada
Collaborating Sponsor
AI-Summary
What this Trial Is About
Chronic spinal pain (CSP) is one of the most common chronic pain conditions globally. Steroid joint injections (SJI) are a routine treatment option for patients with CLBP that is recalcitrant to other treatments. However, SJI has been shown to have limited long-term efficacy with patients often requiring another injection within months to adequately control pain. One option to prolong the analgesic effects of SJI is to use a type of noninvasive brain stimulation called repetitive transcranial magnetic stimulation (rTMS). Previous studies have shown rTMS may be capable of providing long-term pain relief in patients with chronic back pain. However, the literature on rTMS in patients with CSP is limited and no study has explored rTMS in patients receiving recurrent SJI for pain control. In this pilot randomized controlled trial study, we'll be investigating if combining rTMS with SJI in CSP individuals will enhance or prolong the analgesic effects of SJI alone. The investigators hypothesize that a combined rTMS and SJI intervention will be feasible, tolerable, and safe and will have larger and longer-lasting effects on CSP than a sham rTMS and SJI intervention.
CONDITIONS
Official Title
RTMS and Steroid Joint Steroid Injection in Chronic Spinal Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Currently receiving recurrent steroid joint injections for control of chronic spinal pain at the St. Joseph's Health Centre Pain Clinic in London, Ontario, Canada
- Have spinal pain intensity of 4 or higher out of 10 in the week before your most recent steroid joint injection
- Have received at least 2 steroid joint injections within the last 12 months at regular intervals
- Have had a consistent medication regimen for the past 3 months
You will not qualify if you...
- Unable to read, understand, and speak English and unable to give consent
- Known or suspected serious spinal pathology such as tumour, fracture, dislocation, or scoliosis
- Spinal surgery in the past 12 months
- History of uncontrolled mental health conditions
- Meet any specific rTMS-related exclusion criteria listed on the safety screening questionnaire
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
St. Joseph's Health Care London
London, Ontario, Canada, N6A4V2
Actively Recruiting
2
Parkwood Institute (Main Building)
London, Ontario, Canada, N6C 0A7
Actively Recruiting
Research Team
A
Alexandria Roa Agudelo, MLA
CONTACT
K
Keaton Lightfoot, BSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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