Actively Recruiting

Phase Not Applicable
Age: 7Years - 18Years
All Genders
NCT06128746

rTMS Treatment of Spasticity in Children With Cerebral Palsy/ Hemiplegia Due to ABI - a RCT

Led by The University of Hong Kong · Updated on 2026-04-02

20

Participants Needed

1

Research Sites

133 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This RCT aims to investigate the effect of repetitive transcranial magnatic stimulation (rTMS) in treating children with hemiplegoc cerebral palsy. The study will measure any improvement in spasticity after using contra-lesional inhibitory rTMS follow by intensive limb training. Participants will attend a 10-day rTMS treatment sessions, follow by intensive training of the impaired limb. They will also undergo MRI scans before and after the treatment to investiagte the underlying neurophysiological mechanisms that lead to changes clinically by using TMS as well as MR-DKI. Researchers will compare the intervention group and the sham group to see if rTMS could result in improvement of participants' spasticity.

CONDITIONS

Official Title

rTMS Treatment of Spasticity in Children With Cerebral Palsy/ Hemiplegia Due to ABI - a RCT

Who Can Participate

Age: 7Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged between 7 years and 18 years
  • Diagnosis of cerebral palsy with hemiplegia
  • Upper limb spasticity 21 1
  • IQ 21 50
Not Eligible

You will not qualify if you...

  • Any contra-indications to rTMS
  • Severe spasticity (score of 4 or more in Ashworth scale)
  • Uncontrollable epilepsy
  • History of Botulinum toxin A injection in previous 6 months
  • Upper limb casting in previous 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Li Ka Shing Faculty of Medicine

Hong Kong, Hong Kong, Hong Kong, 0000

Actively Recruiting

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Research Team

W

Winnie Wan Yee Tso, MBBS

CONTACT

C

Chai Yin Charlie Fan, MPhil, OTR

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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