Study of Brain Stimulation and Virtual Reality Cognitive Training to Improve Thinking and Mood in Adults 55 and Older with Mild Cognitive Impairment

What this Trial Is About

Researchers are evaluating whether a combination of brain stimulation and cognitive training can improve thinking skills and mood in older adults diagnosed with Mild Cognitive Impairment MCI. This study focuses on using repetitive Transcranial Magnetic Stimulation rTMS along with an immersive virtual reality cognitive training program iVCT to see if these therapies together help more than brain stimulation alone or no intervention. The research also looks at effects on mental health, daily functioning, quality of life, and caregiver burden. Participants will be assigned to one of three groups a control group receiving usual care with no intervention, a group receiving rTMS treatments five days a week for two weeks total 10 sessions, or a group receiving rTMS followed by 30 to 60 minutes of virtual reality cognitive training each day for the same two-week period. All participants will undergo initial assessments before treatment. During the study, participants will complete evaluations at the start, two weeks after treatment, and three months later to measure changes in cognitive abilities, emotional health, daily functioning, and caregiver burden. Tests include the Hopkins Verbal Learning Test and other questionnaires. The study aims to understand both immediate and lasting effects of these therapies over several months, with total participation lasting about three months.

A rTMS and Virtual Reality Based Cognitive Rehabilitation Program for MCI