Actively Recruiting
RUFUS - Group Rumination-focused CBT for Negative Symptoms
Led by Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital · Updated on 2023-10-23
60
Participants Needed
1
Research Sites
152 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Abstract - -- Introduction: Psychosis spectrum disorders are characterized by both positive and negative symptoms, but whereas there is good effect of treatment on positive symptoms, there is still a scarcity of effective interventions aimed at reducing negative symptoms. Rumination has been proposed as an important and fundamental factor in the development and maintenance of symptoms across psychiatric diagnoses, and there is a need to develop effective interventions targeting rumination behaviors and negative symptoms in patients with psychotic disorders. The aim of the current study is to investigate the feasibility and acceptability of group rumination-focused cognitive behavioral therapy (RFCBT) in the treatment of young people with psychosis spectrum disorders as well as investigating potential indications of treatment efficacy. Methods and analysis: The study is a mixed-method clinical randomized controlled pilot trial with a target sample of 60 patients, who are randomized to either receive 13 weeks of group CFCBT or 13 weeks of treatment as usual (TAU). All patients are examined at the start of the project and at the 13-week follow-up. The researcher will compare changes in outcomes from baseline to posttreatment between group CFCBT and TAU. In addition, qualitative analyzes are carried out to explore feasibility and acceptability and to uncover the patients' experience of receiving the intervention.
CONDITIONS
Official Title
RUFUS - Group Rumination-focused CBT for Negative Symptoms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with a psychosis spectrum disorder (ICD-10 F2x)
- At least 8 months remaining in their OPUS treatment
- Presence of rumination behavior with a minimum score of 30 on the Perseverative Thinking Questionnaire (PTQ)
- Danish-speaking
You will not qualify if you...
- Substance abuse or positive symptoms that prevent participation in therapy
- Severe suicidal thoughts or behavior
- Lacking capacity to consent
- Mild, moderate, or severe intellectual disability (IQ ≤ 70)
- Planned changes to antidepressant or antipsychotic treatment noted in medical records
AI-Screening
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Trial Site Locations
Total: 1 location
1
Mental Health Centre Copenhagen
Copenhagen, Denmark
Actively Recruiting
Research Team
L
Lars Clemmensen
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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