Russian Registry to Collect Data on Patients with Very High Triglyceride Levels 10 mmolL or Higher

What this Trial Is About

Researchers are collecting detailed information on patients with extreme hypertriglyceridemia, a condition where triglyceride levels are 10 mmolL or higher. This observational registry, conducted across multiple centers in Russia, aims to understand the clinical, demographic, and genetic features of these patients. The study also looks at current methods used for diagnosis and treatment in everyday medical practice to help guide future research and improve patient care. Patients included in the registry have confirmed extreme hypertriglyceridemia based on at least two separate blood tests. There are no treatments or procedures done as part of the study instead, it records patients clinical progress, lab results, lipid profiles, and any therapies being used as part of their regular care. Genetic testing results are also documented when available. Patients are followed up at least once a year or more often if needed based on their health. Participants continue their usual medical care with their doctors while researchers collect data such as mortality rates, major cardiovascular events, pancreatitis episodes, cholesterol levels, triglyceride levels, and genetic findings over an average of 20 years. Data collection is voluntary and confidential, with patients able to withdraw at any time without affecting their treatment. The study started in November 2025 and will continue through December 2045.

Russian Extreme Hypertriglyceridemia Registry