Actively Recruiting

Age: 18Years +
All Genders
NCT06516406

Ruxolitinib in Primary Myelofibrosis and Secondary to Essential Thrombocythemia or Polycythemia Vera

Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2024-12-05

1055

Participants Needed

26

Research Sites

525 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study is observational multicenter retrospective and prospective cohort study of patients with primary or secondary myelofibrosis who have initiated therapy with ruxolitinib, prescribed as part of the normal course of care and completely independent of study participation. The primary purpose is to determine the impact of clinical and laboratory characteristics of myelofibrosis on the prognosis of patients treated with ruxolitinib, understood as long-term survival.

CONDITIONS

Official Title

Ruxolitinib in Primary Myelofibrosis and Secondary to Essential Thrombocythemia or Polycythemia Vera

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosed with Primary Myelofibrosis or secondary to Essential Thrombocythemia or Polycythemia vera and treated with ruxolitinib according to normal clinical practice
  • Availability of clinical history data prior to starting ruxolitinib therapy
  • Provided informed consent for data collection and processing
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 26 locations

1

Azienda Ospedaliera Annunziata

Cosenza, Calabria, Italy, 87100

Actively Recruiting

2

Grande Ospedale Metropolitano "Bianchi Melacrino Morelli"

Reggio Calabria, Calabria, Italy, 89124

Actively Recruiting

3

Università degli Studi di Napoli Federico II U.O.C. di Ematologia e Trapianti di midollo

Naples, Campania, Italy, 80131

Actively Recruiting

4

IRCCS Policlinico Sant'Orsola

Bologna, Emilia-Romagna, Italy, 40138

Actively Recruiting

5

Università degli studi di Ferrara - Nuovo Polo Ospedaliero di Cona - A.O.U. Arcispedale S. Anna

Ferrara, Emilia-Romagna, Italy, 44124

Actively Recruiting

6

Azienda Ospedaliero-Universitaria di Parma

Parma, Emilia-Romagna, Italy, 43126

Actively Recruiting

7

AUSL di Piacenza - Palazzine Medicine Specialistiche

Piacenza, Emilia-Romagna, Italy, 29121

Actively Recruiting

8

Dipartimento Oncoematologico - AUSL della Romagna

Ravenna, Emilia-Romagna, Italy, 48121

Actively Recruiting

9

Ospedale Infermi di Rimini

Rimini, Emilia-Romagna, Italy, 47923

Actively Recruiting

10

A.O.U. Integrata di Udine

Udine, Friuli Venezia Giulia, Italy, 33100

Actively Recruiting

11

A.O.U. Policlinico Umberto I - Università degli Studi di Roma "La Sapienza"

Rome, Lazio, Italy, 00161

Actively Recruiting

12

Ospedale S. Eugenio

Rome, Lazio, Italy

Actively Recruiting

13

Ospedale Belcolle

Viterbo, Lazio, Italy, 01100

Actively Recruiting

14

IRCCS Azienda Ospedaliera Universitaria "San Martino" - IST

Genoa, Liguria, Italy, 16132

Actively Recruiting

15

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, Lombardy, Italy, 20122

Actively Recruiting

16

Ospedale San Gerardo

Monza, Lombardy, Italy, 20900

Actively Recruiting

17

Ospedale San Luigi Gonzaga - Regione Gonzole

Turin, Piedmont, Italy, 10043

Actively Recruiting

18

Department of Oncology, University of Torino

Turin, Piedmont, Italy, 10124

Actively Recruiting

19

Città della Salute e della Scienza

Turin, Piedmont, Italy, 10126

Actively Recruiting

20

A. O. Ordine Mauriziano di Torino

Turin, Piedmont, Italy, 10128

Actively Recruiting

21

Ospedale "A. Businco" - Dipartimento Scienze Mediche e Sanità Pubblica Università degli Studi di Cagliari

Cagliari, Sardinia, Italy, 09131

Actively Recruiting

22

A.O.U. "Policlinico-V. Emanuele"- P.O. Ferrarotto

Catania, Sicily, Italy, 95124

Actively Recruiting

23

A.O. Ospedali Riuniti Marche Nord - Presidio Ospedaliero San Salvatore

Pesaro, The Marches, Italy, 61122

Actively Recruiting

24

Policlinico S.Maria alle Scotte

Siena, Tuscany, Italy, 53100

Actively Recruiting

25

AOU di Padova

Padova, Veneto, Italy, 35128

Actively Recruiting

26

A.O.U. Integrata Verona

Verona, Veneto, Italy, 37134

Actively Recruiting

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Research Team

F

Francesca Palandri, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Ruxolitinib in Primary Myelofibrosis and Secondary to Essential Thrombocythemia or Polycythemia Vera | DecenTrialz