Actively Recruiting

Age: 18Years - 99Years
All Genders
NCT06797531

RWE Non-Interventional Prospective Study of Ribociclib Effectiveness and Safety in Patients With HR+/HER2- Early Breast Cancer in Saudi Arabia

Led by Novartis Pharmaceuticals · Updated on 2026-02-04

177

Participants Needed

2

Research Sites

170 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a non-interventional, prospective, single-arm, observational study describing the real-world effectiveness, safety, and PRO and HCRU data of ribociclib combined with adjuvant ET under conditions of routine clinical practice in HR+/HER2- EBC in premenopausal, perimenopausal and postmenopausal women, or men in Saudi Arabia.

CONDITIONS

Official Title

RWE Non-Interventional Prospective Study of Ribociclib Effectiveness and Safety in Patients With HR+/HER2- Early Breast Cancer in Saudi Arabia

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed and dated Patient Informed Consent Form (PICF) obtained.
  • Age 18 years or older at the time of consent.
  • Male or female patients with estrogen-receptor-positive and/or progesterone-receptor-positive breast cancer.
  • Male or female patients with HER2-negative breast cancer.
  • Currently receiving ribociclib combined with adjuvant endocrine therapy for up to 6 months prior to enrollment.
  • Diagnosed with American Joint Committee on Cancer (AJCC) Anatomic Stage Group IIA (subset), IIB, or III early breast cancer.
  • Female patients with known menopausal status at consent or initiation of adjuvant endocrine therapy, or male patients.
Not Eligible

You will not qualify if you...

  • Receiving ribociclib-based treatment beyond adjuvant therapy for early breast cancer.
  • Currently participating in any other clinical trials.
  • Previously treated with any other CDK4/6 inhibitor.
  • Refused to sign informed consent.
  • Considered by the investigator unlikely to provide accurate medical history or long-term follow-up information.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Novartis Investigative Site

Riyadh, Saudi Arabia, 11211

Actively Recruiting

2

Novartis Investigative Site

Riyadh, Saudi Arabia, 11426

Actively Recruiting

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Research Team

N

Novartis Pharmaceuticals

CONTACT

N

Novartis Pharmaceuticals

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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