Actively Recruiting
RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty
Led by University of Pittsburgh · Updated on 2025-11-05
150
Participants Needed
3
Research Sites
204 weeks
Total Duration
On this page
Sponsors
U
University of Pittsburgh
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
It is envisioned that multipronged benefits from this pilot work for the UPMC ISD and its members. It is expected the RxWell platform to provide the following benefits: expansion of the use of RxWell to all UPMC ISD members providing peri-operative mood management with advantage of improved peri-operative outcomes, improving saving for the UPMC ISD by hastening the recovery and decreased resource utilization, and addition to the high-value care of UPMC with this holistic approach to patient perioperative care
CONDITIONS
Official Title
RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults older than 18 years
- Scheduled for elective primary total knee or hip replacement surgery at approved UPMC hospitals
- Have moderately high mood disorder symptoms, defined as a T-score of 60 or above on PROMIS Anxiety 4a or Depression 4a short forms
You will not qualify if you...
- Undergoing non-elective surgery or secondary arthroplasty
- Have active delirium, neurocognitive impairment, or severe intellectual disability
- Do not have access to a smartphone or tablet
- Have active alcoholism (daily use of more than 1 liter of wine or 3 or more shots of hard liquor) or daily illicit drug use
- Have severe mood disorders requiring immediate intervention, including suicidal ideation or a PROMIS Depression score over 70
- Have severe anxiety or depression with PROMIS Anxiety or Depression T-score over 70
- Patients needing immediate psychiatric care will be referred appropriately
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
UPMC East
Monroeville, Pennsylvania, United States, 15146
Actively Recruiting
2
UPMC Shadyside
Pittsburgh, Pennsylvania, United States, 15232
Actively Recruiting
3
UPMC Passavant
Pittsburgh, Pennsylvania, United States, 15237
Actively Recruiting
Research Team
A
Ata Murat Kaynar, MD, MPH
CONTACT
C
Carly Riedmann, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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